DOI: 10.29245/2578-2967/2018/6.1143 View / Download Pdf View Full Text
Joseph A. Di Como1, Christina W. Lee2, Sharon M. Weber2*
Department of Surgery, Conemaugh Memorial Medical Center, Johnstown PA, USA
Department of Surgery, University of Wisconsin, Madison WI, USA
Igor M. A. Melo, Eliane A. Ribeiro, Renata A. Canevari*
Laboratório de Biologia Molecular do Câncer, Instituto de Pesquisa & Desenvolvimento (IP&D), Universidade do Vale do Paraíba (UNIVAP), São José dos Campos, São Paulo, Brasil
Human papillomavirus (HPV) infection is the most common sexually transmitted disease worldwide and several studies have proven the close relationship between HPV and the development of cervical cancer. Several tests are currently performed for early and reliable diagnosis, in which the cervical cytology evaluation by the Papanicolaou method is highlighted. However, errors in the collection and misinterpretation of cell differentiation degree in smear by the pathologist result in incorrect or inaccurate results. Considering these points, it is of utmost importance to develop new technologies that perform accurate and reliable diagnosis and that present financial advantages and accessibility. Currently, molecular biology assays are excellent detectors of viral DNA, but it presents disadvantages, such as the need for high financial resources to gain access. Therefore, this review has the objective of highlighting the main diagnostic techniques that are already being used, such as specific kits for the detection of high-risk HPVs, or methodologies that are still in the study phase, but which already present good results, such as the application of physical FTIR spectroscopy principles and ultrasensitive biosensors.DOI: 10.29245/2578-2967/2018/6.1132 View / Download Pdf View Full Text
Steven S. Coughlin1,2*, Lee Caplan3, Lufei Young4
1Department of Population Health Sciences, Medical College of Georgia, Augusta University, Augusta, GA
2Research Service, Charlie Norwood Veterans Affairs Medical Center, Augusta, GA
3Morehouse College of Medicine, Department of Community Health and Preventive Medicine, Atlanta, GA
4College of Nursing, Augusta University, Augusta, GA
Background: Patient portals and other Internet-based technologies have been increasingly used to improve cancer care coordination. Patient portals may introduce special considerations in oncology populations where longitudinal outpatient care is often more intensive than in most other specialties.
Methods: This article, which is based upon bibliographic searches in PubMed, reviews the literature on web portal use by cancer patients. Articles published in English from 2000 to August 2018 were identified using the following MeSH search terms and Boolean algebra commands: web portal AND cancer. Information obtained from bibliographic searches (title and topic of article, information in abstract, and keywords) was used to determine whether to retain each article identified in this way.
Results: A total of 263 article citations were identified in the bibliographic searches. Of these, 10 met the eligibility criteria. A variety of study designs were used including focus groups, usability testing, in-person interviews, questionnaire surveys, retrospective cohort, and non-randomized trial. Cancer patients had reached modest levels of portal use. Increased portal use has been associated with younger age, white race, and higher socioeconomic status. Most cancer patients used portals to look up testing results and provide notes, but had difficulty in interpreting the results appropriately.
Conclusions: Our study adds to the growing evidence that patient portals play a significant role in promoting self-management in cancer survivors. Additional studies are needed to determine factors influencing portal use, so effective interventions can be developed to enhance portal use.DOI: 10.29245/2578-2967/2018/6.1154 View / Download Pdf View Full Text