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Christina Ng Van Tze^1*, Henry Fitzgerald², Akhtar Qureshi³, Huck Joo Tan³, May Lee Low⁴, Mun Kit Lim⁴, Vui Chee Lo¹

Colorectal cancer is a major cause of morbidity and mortality worldwide. It has been identified as the most common cancer in men and second most common cancer in women in Malaysia. This mini-review is meant to present the current state and overview of colorectal cancer in Malaysia. Our efforts through EMPOWERED, The Cancer Advocacy Society of Malaysia to reduce the toll of colorectal cancer through a customised annual Colorectal Cancer Awareness, Screening and Treatment Project with high compliances are also briefly summarised.

Diaddin Hamdan^1,2, Anne Janin^2,3*, Guilhem Bousquet^{2, 4, 5#}

Francesco Gentile¹, Jack A. Tuszynski^1,2 and Khaled H. Barakat³*

Dinesh Chandra Doval^1*, Atika Dogra^{2 3}

Laurent Schwartz

Assistance Publique des Hôpitaux de Paris, Avenue Victoria 75003 Paris, France

A first patient with metastatic adenocarcinoma of the pancreas has decided, on his own, to refuse chemotherapy but to treat himself with lipoïc acid, hydroxycitrate combined with oral ingestion of chlorine dioxide. His blood tests and radiological examinations have almost normalized and the disease is stable at 18 months. Another patient with hormone resistant metastatic prostate cancer has experienced a sharp drop in PSA level as well as improved medical condition. From extensive literature review, the mechanism of action of chlorine dioxide is unknown. It is our hypothesis (albeit unproven) that chlorine dioxide results in tumor cell acidification of the alkaline pH of cancer cells.